منابع مشابه
Recent developments in vertical transmission of ZIKA virus
Recently Zika virus (ZIKV) has been the focus of much attention, primarily because of its association with an increased incidence in microcephaly. Although ZIKV was initially discovered in a sentinel rhesus monkey in Uganda [1], its range includes Africa, Southeast Asia, and Latin America. Much of the recent concern regarding ZIKV arises from a dramatic rise in microcephaly that has been report...
متن کاملVertical Transmission of Zika Virus in Aedes aegypti Mosquitoes
Previous experimental studies have demonstrated that a number of mosquito-borne flavivirus pathogens are vertically transmitted in their insect vectors, providing a mechanism for these arboviruses to persist during adverse climatic conditions or in the absence of a susceptible vertebrate host. In this study, designed to test whether Zika virus (ZIKV) could be vertically transmitted, female Aede...
متن کاملVertical transmission of BK virus in pregnancy: A narrative review
Background: Primary infection with the BK virus occurs in the tonsils and is transmitted to other tissues and organs, especially the kidneys, by infecting monocytes. Infection with this virus is rarely associated with clinical disease but reactivating the virus in people who have a suppressed immune system can cause kidney or bladder damage. Due to the importance of activating the BK virus in s...
متن کاملVertical Transmission of Zika Virus by Aedes aegypti and Ae. albopictus Mosquitoes
To determine the potential role of vertical transmission in Zika virus expansion, we evaluated larval pools of perorally infected Aedes aegypti and Ae. albopictus adult female mosquitoes; ≈1/84 larvae tested were Zika virus-positive; and rates varied among mosquito populations. Thus, vertical transmission may play a role in Zika virus spread and maintenance.
متن کاملInhibition of autophagy limits vertical transmission of Zika virus in pregnant mice
Zika virus (ZIKV) infection during pregnancy leads to devastating fetal outcomes, including intrauterine growth restriction and microcephaly. Greater understanding of mechanisms underlying ZIKV maternal-fetal transmission is needed to develop new therapeutic interventions. Here, we define an important role for the autophagy pathway in ZIKV vertical transmission. ZIKV infection induced autophagi...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-19526-4